Proton range verification detectors

Award

Value

£120,290

Classifications

  • Detection apparatus

Tags

  • award
  • contract

Published

3 years ago

Description

The PRECISE proton therapy research group at the University of Manchester and the Christie NHS Foundation Trust is developing a system to verify range during proton beam therapy treatments. Range uncertainty is arguably one of the biggest challenges in proton therapy. Range uncertainty arises from a number of sources: imaging, dosimetry, stopping powers, however, the largest uncertainty is always the patient. Patient setup, highly heterogeneous tissue, implants, or bone/tissue interfaces as well as anatomical changes during treatment can all influence proton range and thus, treatment outcomes. The full potential of proton beam therapy, particularly when there are organs-at-risk in the vicinity of the tumour, cannot be exploited unless these uncertainties are reduced or mitigated.
One possible method of determining proton range is through the detection of the prompt gamma-rays that are emitted naturally during therapy. It has been shown experimentally that the maximum intensity of these prompt gamma rays correlates well with the Bragg peak and end-of-range. By detecting these prompt gamma-rays and determining their origin the proton beam range could be established.
The system being developed is based on an array of scintillator detectors coupled with an image reconstruction algorithm based on gamma-ray coincidences. The detectors of choice are LaBr3 scintillators which exhibit good energy and timing resolution for the detection of the high energy gamma-rays emitted. The typical gamma-ray energy range of interest is 2 – 8 MeV so large crystal, 38.1 mm (1.5”) diameter and 50.8 mm (2”) long, detectors are required in order to obtain full energy photo peaks. As the reconstruction algorithm utilises gamma-ray coincidences, the detectors need to have an energy resolution of 3.5% or less at 662 keV and a coincidence resolving time of 0.5 ns or less. Ideally we are also looking for the detectors to have an anode pulse rise time of 0.8 ns or less and an electron transit time of 16 ns or less.

Documents

Premium

Bypass the hassle of outdated portals. Get all the information you need right here, right now.

  • Contract Agreement

    The official contract terms, conditions, and scopes of work.

    Download
  • Award Notice

    Details on the tender award and selected suppliers.

    Download

Similar Contracts

Open

Wrexham Smart Towns Expansion – LoRaWAN/ IOT Sensors and Associated Hardware Framework

Wrexham County Borough Council wish to establish a Framework for LoRaWAN IOT sensors and other associated hardware for the expansion of the Wrexham Smart Towns initiative. The SMART Towns initiative was launched in 2022 and has proven highly successful. It is hosted within the Regeneration team at Wrexham County Borough Council (WCBC), links to the Council plan and is backed by the Welsh Government. WCBC is now seen as one of the leading authorities in the UK on implementing IOT (Internet of Things) sensors to obtain data to help the Council make better informed decisions. These sensors obtain data sets such as footfall, dwell time, air quality and traffic data etc. Progress has seen some key benefits to the local authority, including the ability to make efficiencies. The use of moisture sensors within the city centre has provided data that ensures the local authority embeds a smarter way of working, as it only has to water necessary plant beds. The authority is now looking to expand on the success of the pilots and explore more possible projects, such as flood monitoring (flood risk team), air quality (open spaces team), road temperature sensors to identify savings on gritting, sensors to highlight potential savings on energy, and the technology is to be introduced to parts of Social Care to ensure SMART is a way of life to ensure the safety of our residents Please see the Invitation to Tender (ITT) document, pricing list, appendices and other supporting documents for full details of the proposed work. These have been published and are available on the eTenderWales (Bravo Solutions) online e-sourcing portal, which can be accessed through this web address: https://etenderwales.bravosolution.co.uk/. You will need to be registered as a supplier on both Sell2Wales/FTS and eTenderWales. To access and download the documents you will need to be logged into eTenderWales and search for the Invitation to Tender (ITT). You can look up the tender with the following reference: project_59662, itt_118024 - Wrexham Smart Towns Expansion – LoRaWAN/ IOT Sensors and Associated Hardware Framework. Interested suppliers may ask clarification questions though eTenderWales. If you wish to tender for the work, your tender submission will need to be uploaded though eTenderWales.

Katy Reed

Published 3 weeks ago

AI Bid Assistant

Our AI-powered tool to help you create winning bids is coming soon!

View Contract Source Save Contract

Timeline complete

Publish
Bid
Evaluate
Award
Complete